- This web site describes various icosahedral virus capsid structures in the
Protein Data Bank (PDB) in terms of their complete capsids, detailed structural and computational analysis
 - The protomeric
(asymmetric unit) coordinates were transformed and stored
in a single icosahedral convention (2(Z)-3-5-(X)2).
The icosahedron to the right displays this alignment.
Coordinates (sometimes) were further processed by rearranging the
nucleic acid residues, hetero atoms, and water molecules (if present) at the
end of the protein chains for the ease of further analysis.
- Structures are classified in terms of their quasi-symmetry
(e.g. T=3, T=4, T=7) and pseudo-symmetry (e.g., P=3).
- Tools are being developed to study the capsids in terms of structural, energetic and assembly aspects . The
derived results have been made available through this website.
- The site is being developed as part of the training, service and
dissemination component of the NIH Research Resource: Multiscale Modeling Tools for Structural Biology (MMTSB).
- You are very welcome to download the figures
and the data presented throughout this website. Please, however, cite
the reference (below) and the VIPER website when you use them in the publications/ posters/ presentations. Thanks for your cooperation.
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Reference Publication |
VIrus Particle ExploreR (VIPER), a Website for
Virus Capsid Structures and Their Computational Analyses.
Reddy V, Natarajan P, Okerberg B, Li K, Damodaran K, Morton R, Brooks III C, Johnson J. 2001. J. of Virology 75:11943-11947.
Download the Reprint (PDF)
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